Oral controlled-release drug delivery technologies have the ability to improve the performance of a wide variety of existing pharmaceutical compounds. The therapeutic effect of a drug compound will typically vary according to its bloodstream concentration. When the concentration is too low, efficacy may be reduced and when it is too high, side effects may increase.
For any drug compound, there is an optimal range of concentrations, in which the balance between efficacy and side effects is optimized. In traditional drug tablets without controlled-release, blood levels of the drug tend to rise quickly after administration, reach a peak and then drop fairly rapidly, thus requiring frequent dosing. Side effects may also occur at the high peak blood levels experienced.
Controlled-release technologies allow a drug compound’s concentration to be maintained within the therapeutic range, extending its therapeutic effect over a prolonged period and often improving its safety profile. This added convenience may increase patient compliance and therefore improve medical outcomes.
Our current oral controlled release technologies include our Tri-Layer Tablet and our Quick Release Wafer